N-Methyl-N-(2,2,2-trifluoroethyl)aMine HCl

N-Methyl-N-(2,2,2-trifluoroethyl)aMine HCl - Names and Identifiers

Name	2,2,2-trifluoro-N-methylethanaminato hydrochloride (1:1)
Synonyms	2,2,2-Trifluoro-N-MethylethanaMine HCl Methyl(2,2,2-trifluoroethyl)aMine, HCl N-Methyl-N-(2,2,2-trifluoroethyl)amine HCl N-Methyl-N-(2,2,2-trifluoroethyl)aMine HCl 2,2,2-TRIFLUORO-N-METHYLETHANAMINIUM CHLORIDE N-Methyl-2,2,2-trifluoroethylamine Hydrochloride N-methyl-N-(2,2,2-trifluoroethyl)amine hydrochloride
CAS	2730-52-1
InChI	InChI=1/C3H6F3N.ClH/c1-7-2-3(4,5)6;/h7H,2H2,1H3;1H

N-Methyl-N-(2,2,2-trifluoroethyl)aMine HCl - Physico-chemical Properties

Molecular Formula	C3H7ClF3N
Molar Mass	149.54
Melting Point	>200 °C (sublm)(Solv: ethanol (64-17-5))
Boling Point	67.8°C at 760 mmHg
Vapor Presure	138mmHg at 25°C
Storage Condition	Inert atmosphere,Room Temperature

N-Methyl-N-(2,2,2-trifluoroethyl)aMine HCl - Risk and Safety

Hazard Class

IRRITANT

N-Methyl-N-(2,2,2-trifluoroethyl)aMine HCl - Introduction

2,2, hydrochloride (1:1) (2,2, hydrochloride (1:1)) is an organic compound whose molecular formula is CF3CH2NHCH3 · HCl. The following is a brief description of its nature, use, preparation and safety information:

Nature:
-Appearance: usually white solid powder
-Molecular weight: about 149.53g/mol
-Melting point: About 154-160 ° C
-Solubility: Soluble in polar solvents such as water and ethanol

Use:
- 2,2, hydrochloride (1:1) is often used as a precursor for fluorinated compounds in the synthesis.
-It can be used to synthesize biologically active organic molecules and pharmaceutical intermediates.
-Due to its special chemical properties, it can participate in many organic reactions, such as nucleophilic substitution, electrophilic substitution, acylation, etc.

Method:
2,2, hydrochloride (1:1) is prepared by various methods. The following is a common synthetic route:
ethyl 2,2, 2-trifluoroacetate (CF3CH2CO2Et) reacts with methylamine (CH3NH2) to form N-methyl-N-2,2,2-trifluoromethylacetamide, it is then treated with hydrogen chloride (HCl) to form its hydrochloride salt.

Safety Information:
- 2,2, hydrochloride (1:1) powder should be avoided from inhalation and contact with the skin, as it may cause irritation and injury to the human body.
-Personal protective equipment such as chemical safety gloves, goggles and protective clothing are recommended for use or manipulation.
-Pay attention to comply with Good Laboratory Practices during operation to ensure a safe and reliable working environment.

Last Update：2024-04-09 21:04:16